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Plant-based · Two capsules daily · 30-day supply
The UK's first microplastic binding supplement.
Plant-based chitosan from mushrooms, paired with four plant polyphenols. Two capsules a day, in a reusable steel tin.
Tiny plastic. Big problem.
Microplastics are already in us.
Scientists have now found tiny plastic particles in human blood, lungs and even the brain.
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lung samples contained microplastics
Jenner et al., 2022~50%
more microplastics measured in brain samples from 2024 than from 2016
Nihart et al., 2025How were these measured?
Blood
Amsterdam researchers tested blood from 22 healthy adult donors. PET, the plastic used for drinks bottles, was the most common.
Lungs
A Hull York Medical School team analysed lung tissue from living surgery patients, including the lowest parts of the lungs.
Brain
US researchers measured micro- and nanoplastics in brain tissue from autopsies carried out in 2016 and 2024. Levels were about 50% higher in the 2024 samples. It's a small study, and other scientists have questioned the measurement method, so treat it as an early signal.
These are small studies of exposure, not tests of Polygone. They do not establish what Polygone can do.
No complicated rituals
How it works.
Two capsules daily.
Take two capsules a day with water.
Chitosan from mushrooms.
A natural fibre, designed to bind particles in the gut so they're carried out naturally.
Four plant polyphenols.
Four plant polyphenols round out the formula.
The science
What the research says
Chitosan is a natural fibre that forms a gel in the stomach. Three early studies have looked at what happens to microplastics when it's taken with food.
26%
Fewer microplastics measured in blood
11 healthy adults took 0.8g of chitosan a day for 15 days. The microplastics measured in their blood fell by 26% on average. A matched group of 10 who didn't take it saw no significant change.
Studied crustacean-derived chitosan, not Polygone.
Cornelli et al., Journal of Xenobiotics, 202647%
More microplastics passed naturally
10 healthy volunteers ate the same standard meal twice, a week apart, the second time with 0.8g of chitosan. Their stool samples contained 47% more microplastic particles on average after the chitosan meal.
Studied crustacean-derived chitosan, not Polygone.
Casella et al., Foods, 202550%
Less plastic left in the gut
Rats fed plastic particles for a week kept about half as much in their intestines when chitosan was added to their diet (6% vs 12%). Chitosan outperformed the three other fibres tested.
Liu & Shimizu, Scientific Reports, 2025The straight-up list
What's inside.
- Chitosan (made from mushrooms)
- Four plant polyphenols
- Vegetable capsule
And absolutely not
What's not.
- Animal products
- Gelatine
- Plastic packaging
- Fillers you don't need
Keep the good bit
Plastic-free, down to the lid.
A steel tin you keep. Plastic-free paper refills that post through your letterbox. Less packaging theatre, more common sense.
Simple pricing
Your first tin. Then refills.
Your first order comes in a steel tin you keep. After that, plastic-free paper refills post through your letterbox.
One-off tin
£34.99
60 capsules · 30-day supplyFounding offer
Subscribe & refill
Founding member price
£23.99/month
Standard subscription price: £29.99/month
20% off the standard subscription. For the first 200 subscribers. Discount continues while you remain subscribed.
60 capsules · 30-day supplyJoin the waitlistNo payment today. We'll email you when subscriptions open.
Plant-based
UK-based company
Plastic-free packaging
Made in small batches
Fair questions
The useful bits.
What does Polygone do?
Polygone is built around chitosan, a natural fibre studied for its ability to bind microplastics in the gut, alongside four plant polyphenols.
Is it plant-based?
Yes. It uses fungal rather than shellfish-derived chitosan, and the capsule is plant-based.
Why chitosan from mushrooms?
Our chitosan comes from mushrooms: it's fungal rather than shellfish-derived chitosan.
How do I take it?
Take 2 capsules daily with water.
Who shouldn't take it?
If you're pregnant, breastfeeding, taking medication or have a medical condition, please consult your doctor first. For adults.
When do you launch?
Soon. Join the list and you'll be first to know the date.
What does founding member mean?
The first 200 subscribers get 20% off their monthly refill for life, while they remain subscribed.